Hydrocortisone Acetate should be applied in a small quantity to the affected area 2 or 3 times daily.
Indications
The anti-inflammatory activity of Topicort is its main therapeutic property. It also has immunosuppressant and antimitotic actions. Topicort is indicated in:
Hydrocortisone binds to the cytosolic glucocorticoid receptor. After binding the receptor the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes.
Hydrocortisone Acetate should be applied in a small quantity to the affected area 2 or 3 times daily.
Infections: bacterial, viral, fungal.Skin ulcers.Hypersensitivity to the preparation.
Topicort 1% cream is usually well-tolerated, but if signs of hypersensitivity appear, application should be stopped.
There is inadequate evidence for safety in human pregnancy. It is recommended that topical corticosteroids should not be used extensively during pregnancy. It is highly unlikely that sufficiently high blood levels of Hydrocortisone are achieved during topical therapy to reach breast milk.
In infants and children, long-term continuous topical therapy should be avoided where possible, as adrenal suppression can occur. As with all corticosteroids, prolonged application to the face is undesirable.
Acute overdosage is very unlikely to occur, however, in the case of chronic overdosage or misuse, the features of hypercorticism may appear and in this situation topical steroids should be discontinued.
Other Topical corticosteroids
Store in a cool and dry place, away from light. Keep out of reach of children.
