Antacids containing magnesium, aluminium or calcium may decrease absorption of Rutix. Iron or Zinc may decrease oral absorption of Rutix.
Ofloxacin containing ofloxacin is a synthetic 4-fluoroquinolone antibacterial agent with bactericidal activity against a wide range of Gram-negative and Gram-positive organisms. Ofloxacin is thought to exert bactericidal effect by inhibiting DNA gyrase, an essential enzyme that is a critical catalyst in the duplication, transcription and repair of bacterial DNA.
Antacids containing magnesium, aluminium or calcium may decrease absorption of Rutix. Iron or Zinc may decrease oral absorption of Rutix.
Ofloxacin should not be used in-patients with known hypersensitivity to 4-fluoroquinolone antibacterials. It is contraindicated in-patients with a history of epilepsy or with a lowered seizure threshold. Ofloxacin is usually contraindicated in children or growing adolescents and in pregnant or breast feeding women.
Rutix tablet is generally well tolerated and clinical side-effects of Rutix has been quite low. Among the adverse effects gastrointestinal and central nervous systems' reactions are common. Nausea, rash, vomiting, abdominal pain, diarrhoea and gastrointestinal distress are the gastrointestinal adverse effects. Common central nervous system reactions are headache, dizziness and insomnia.
Eye: Transient ocular irritation, burning, stinging, redness, itching or photophobia have been reported.
Ear: Mild irritation or mild discomfort in the ear may occur. Symptoms of an allergic reaction include rash, itching, swelling or trouble breathing.
The safety of ofloxacin during pregnancy has not been established. Ofloxacin may enter breast milk but data are not available.Precautions & WarningsPatients being treated with Rutix should not expose themselves unnecessarily to strong sunlight and should avoid UV rays. Caution is recommended if the drug is to be used in psychotic patients or in-patients with a history of psychiatric disease.Prolonged use of eye drops & ear drops may result in overgrowth of non-susceptible organisms and secondary infection respectively.
4-Quinolone preparations, Aural Anti-bacterial preparations
Store between 15-30°C. Protect from light.
