Paloset 0.075 mg/1.5 ml Injection

Paloset indicated in-

• Acute and delayed nausea and vomiting
• Uncontrolled nausea and vomiting
• Chemotherapy-induced nausea and vomiting (CINV): Acute CINV resulting in on the day of treatment with certain types of chemotherapy
• Delayed CINV resulting in on days later with certain types of chemotherapy
• Radiotherapy-induced nausea and vomiting (RINV)
• Post-operative & Post-discharge nausea and vomiting (PONV & PDNV).

Contraindications

Palonosetron is contraindicated in patients known to have hypersensitivity to the drug or any of its components.

Side Effects

The most common adverse reactions are headaches and constipation.

Pregnancy & Lactation

Pregnancy category 'B'. It is not known whether Palonosetron is excreted in breast milk.

Use in Special Populations

Use in elderly patients: No dosage adjustment is recommended in elderly patients >65 years of age.

Use in Children: (1 month to 10 years): A single IV dose at 20 mcg/kg body weight. Which maximum dose is 1.5 mg.

Use in patients with impaired renal and hepatic function: No dosage adjustment is recommended in patients with renal and hepatic dysfunction.

Overdose Effects

There is no known antidote to Paloset. Overdose should be managed with supportive care.

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Store in a cool & dry place, protected from light.