Fliban 100mg Tablet is indeed a medication used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women.
Fliban tablet is indicated for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to:
The mechanism of action of Flibanserin in the treatment of premenopausal women with hypoactive sexual desire disorder is not known. Flibanserin demonstrated high affinity for 5-HTIA & 5-HT2A receptors, showing agonist activity on 5-HTIA & antagonist on 5-HT2A, resulting in lowering of serotonin in the brain as well as effect on increasing norepinephrine and dopamine neurotransmitters.
Recommended dosage of Flibanserin: 100 mg taken once daily at bedtime
Pediatric Use: Not recommended in patients below 18 years of age.
Geriatric Use: Flibanserin is not indicated for use in geriatric patients. Safety and effectiveness have not been established in geriatric patients.
Oral Contraceptives and Other Weak CYP3A4 Inhibitors: Increases Fliban exposures and incidence of adverse reactions.
Strong CYP2C19 Inhibitors: Increases Fliban exposure which may increase risk of hypotension, syncope, and CNS depression.
CYP3A4 Inducers: Use of Fliban not recommended; Fliban concentrations substantially reduced.
Digoxin: Increases digoxin concentrations, which may lead to digoxin toxicity. Increase monitoring of digoxin concentrations.
Flibanserin is contraindicated:
Most common side effects are Dizziness, Somnolence, Nausea, Fatigue, Insomnia, Dry mouth.
There are no studies of Flibanserin in pregnant women to inform whether there is a drug-associated risk in humans.
Patients with pre-syncope should immediately lie supine and promptly seek medical help if symptoms do not resolve.
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
