Alice is indicated for the treatment of onchocerciasis due to the nematode parasite Onchocerca volvulus.
Alice is indicated for the treatment of onchocerciasis due to the nematode parasite Onchocerca volvulus.
Alice tablet is indicated for the treatment of-
Ivermectin selectively binds and with high affinity to glutamate-gated chloride ion channels, which occur in invertebrate nerve and muscle cells leading to an increase in the permeability of cell membranes to chloride ions with hyperpolarization of the nerve or muscle cell and, ultimately, death of the parasite.
Post-marketing reports of increased INR (International Normalized Ratio) have been rarely reported when Alice was co-administered with warfarin.
It is contraindicated in patients who are hypersensitive to any component of this product.
Pregnancy Category C. Ivermectin does not appear to be selectively fetotoxic to the developing fetus. There are, however, no adequate and well-controlled studies in pregnant women. Ivermectin should not be used during pregnancy since safety in pregnancy has not been established.
Nursing Mothers: Ivermectin is excreted in human milk in low concentrations. Treatment of mothers who intend to breast feed should only be undertaken when the risk of delayed treatment to the mother outweighs the possible risk to the newborn
Pediatric Use: Safety and effectiveness in pediatric patients weighing less than 15 kg have not been established.
Geriatric Use: Clinical studies of Alice did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.
Anthelmintic
Keep in a dry place, below 30°C. Protect from light. Keep out of the reach of children.
